Prenatal Cannabis Use and Maternal Pregnancy Outcomes
The relative lack of research on how prenatal cannabis use is associated with maternal health vs offspring health is notable. This study leveraged data from a large health care system to examine the associations between cannabis use during early pregnancy and maternal health, adjusting for clinical and sociodemographic factors. Prenatal cannabis use was associated with greater risk of gestational hypertension, preeclampsia, GWG outside of guidelines, and placental abruption and lower risk of GD. Prenatal cannabis use was associated with a greater risk of eclampsia, but the result did not reach statistical significance, possibly due to the rarity of this outcome. Associations were slightly stronger for most outcomes when examining cannabis use measured by toxicology testing vs self-report, but the pattern was similar across exposure definitions.